منابع مشابه
Approaching atomic resolution in crystallography of ribosomes.
POSSIBLE FUNCTIONAL RELEVANCES IN THE RECONSTRUCTED MO ELS ........................... 86 Approximate Shapes of the Ribosomal Subunits Within the Assembled 70S Ribosome 86 Tentative Assignments for the Path of the Nascent Proteins and for the Site Qf the Biosynthetic Reaction .................................................................................... 86 Crystallizable Complexes Mimicki...
متن کاملCrystallography of ribosomes: attempts at decorating the ribosomal surface.
Crystals of various ribosomal particles, diffracting best to 2.9 A resolution were grown. Crystallographic data were collected from shock frozen crystals with intense synchrotron radiation at cryo temperature. For obtaining phase information, monofunctional reagents were prepared from an undecagold and a tetrairidium cluster, by attaching to them chemically reactive handles, specific for sulfhy...
متن کاملThe interplay between X-ray crystallography, neutron diffraction, image reconstruction, organo-metallic chemistry and biochemistry in structural studies of ribosomes.
Crystals of ribosomes, their complexes with components of protein biosynthesis, their natural, mutated and modified subunits, have been subjected to X-ray and neutron crystallographic analyses. Electron microscopy and 3-dimensional image reconstruction, supported by biochemistry, genetic, functional and organo-metallic studies were employed for facilitating phasing of the crystallographic data....
متن کاملNascent Ribosomes
The conversion of a ribosomal RNA transcript to a cytoplasmic ribosome requires hundreds of accessory RNA and protein factors. Two papers published recently in Molecular Cell provide first looks at the association of these processing factors with the intermediates in ribosome synthesis (Harnpicharnchai et al., 2001; Bassler et al., 2001).
متن کاملSynthetic ribosomes
1 describes the design, synthesis and operation of an artificial small-molecule capable of synthesizing peptides in a sequence-specific manner. The design of this artificial molecular machine was, in the author's own words, " inspired by the ribosome " ; 2 with several elements analogous to ribosomal protein synthesis (Fig. 1). The tRNA's of conventional translation are substituted by amino aci...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 1993
ISSN: 0108-7673
DOI: 10.1107/s0108767378099900